Scientific Officer

2 weeks ago


Cape Town, South Africa Cape Town Immunology Laboratory (Hutchinson Center Research Institute of South Africa) Full time

**Position Purpose**:
The Scientific Officer (SO) will be responsible for flow cytometry other data analysis for clinical studies. S/he will design experiments, conduct some hands-on research and assist with experimental troubleshooting as required, ensuring that laboratory clinical assays meet appropriate quality level standards. S/he will write laboratory documents for assays being conducted for clinical trials. S/he will report findings at scientific meetings and other venues and assist with manuscript, grant and report writing.

**Laboratory Research and Data Analysis (70%)**
- Perform advanced multiparameter flow cytometry and other types of assays, troubleshooting and assisting with resolution of any issues.
- Perform advanced analysis of flow cytometry and other types of data generated in the lab.
- Lead efforts to develop, qualify or validate clinical assays to be fit-for-purpose for clinical trial testing, including the writing of qualification or validation reports.
- Ensure that qualified or validated assays remain of the highest quality by leading good lifecycle management practices such as overseeing critical reagents, performing reagent bridging, assay trending and root-cause investigations.
- Coordinate establishment and implementation of new techniques in the laboratory, conducting studies to answer immunological questions related to vaccination.
- Follow, update, modify and write lab protocols, standard operating procedures (SOPs), study
- specific procedures (SSP) and other study-related documents/reports.
- Assist with training of lab and clinic staff in lab techniques and/or theory, as required.

**Project Management (20%)**
- Work closely with the Endpoints team to ensure seamless execution of sample analysis.
- Manage projects, interfacing with lab, the flow cytometry specialist, statistical and clinic staff as required.
- Work with laboratory leadership to ensure the success of the overall study goals.

**Laboratory Operations (5%)**
- Share on-call duties with lab personnel to respond to equipment alarms in a timely manner after normal work hours (off-hours).
- Attend and participate in appropriate laboratory meetings.
- Contribute to the development of the laboratory environment (e.g. laboratory safety).

**Quality Assurance (QA) (5%)**
- Conduct all work according to Good Clinical Laboratory Practice (GCLP) guidelines and auditable
- standards, ensuring accurate and timely reporting and record keeping.
- Assist with review of laboratory records, ensuing compliance with GCLP guidelines.

**Salary**: From R35,000.00 per month



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