senior python developer jobs in Cape Town

1,000 senior python developer job listings in South Africa. Find daily updated positions from leading job boards.


  • cape town, western cape, South Africa Blacksmith Agency LLC Full-time

    About The Role Blacksmith Agency is hiring Sales Development Representatives across South Africa who are hungry to open doors and drive pipeline. As Senior Business Development Representative at Blacksmith, you own the top of the funnel: researching, sourcing and booking meetings with qualified decision makers, and creating the first impression of Blacksmith...


  • cape town, western cape, South Africa Hire Resolve Full-time

    A tech recruitment agency is seeking an experienced C#. NET Developer to join their team in Cape Town, South Africa. The ideal candidate will have over 7 years of experience and possess a relevant IT degree or diploma. Proficiency in C#, MVC, Web API,. NET Framework & Core, GIT, LINQ, Entity Framework, and MSSQL Server is required. This is a great...


  • cape town, western cape, South Africa Placements24 Full-time

    Placements24 is seeking an experienced Lead Solar Project Developer to spearhead the identification, acquisition, and development of solar projects globally from a home office. You will own the full lifecycle from site assessment to offtake agreements, working with internal teams and external partners in a remote setting. The role requires a senior...


  • Cape Town, Western Cape, South Africa BruntWork Full-time

    Our client is a high-end custom window treatment company in New York City, specializing in premium shades, blinds, and drapery for residential and commercial projects. They are looking for an experienced Senior B2B Business Development Specialist (Real Estate) professional to drive commercial growth by identifying new business opportunities and connecting...


  • Cape Town, Western Cape, South Africa Hire Resolve Full-time

    A fast-growing international IT consultancy in Cape Town is seeking a Senior C# ASP.Net Developer. The role includes developing applications using C# and ASP.NET, mentoring junior developers, and solving complex problems. Candidates should possess a Bachelor's Degree in Computer Science or related fields and substantial knowledge of web technologies like...

  • Senior AI Developer

    11 hours ago


    Cape Town, Western Cape, South Africa Pype Full-time

    Pype in Cape Town is seeking a Senior AI Developer to build production AI systems in a regulated payments environment. This hands-on role requires shipping LLM-based solutions beyond simple prompts and applying AI across the delivery lifecycle.You will design services in Python and .NET, build content embedding and retrieval pipelines for RAG, and implement...


  • Cape Town, Western Cape, South Africa Apply-USA Full-time

    Apply-USA is seeking a Software Developer in South Africa with 5+ years of experience to contribute to development efforts and maintain high-quality software. You will work on day-to-day tasks, ensure proper documentation, and support a collaborative team environment.The role requires independent work, effective time management, and strong written and verbal...


  • Cape Town, Western Cape, South Africa Placements24 Full-time

    Placements24 is seeking a Senior Civil Engineer for a fully remote role in South Africa. Focused on site development and stormwater management, you will lead grading, drainage and utility coordination while collaborating with remote teams. Proficiency with AutoCAD Civil 3D and stormwater tools is required.The ideal candidate has 7+ years of experience, ECSA...


  • Cape Town, Western Cape, South Africa Blacksmith Agency LLC Full-time

    Blacksmith Agency Llc is seeking a Senior Corporate Legal Advisor to support business development initiatives in a fully remote capacity. You will provide strategic legal counsel on M&A, joint ventures, strategic partnerships, and corporate restructuring, and negotiate complex agreements to mitigate risk.The role requires an admitted High Court SA attorney...


  • Cape Town, Western Cape, South Africa Jobgether Full-time

    This position is listed on behalf of a partner company, which manages all applications and next steps. Our partner is looking for a Senior Java Developer (Data | AWS) (IT Consultant) based in South Africa.Join a high-impact technology engagement focused on building and maintaining scalable, cloud-native data services. In this hands-on backend engineering...


  • Cape Town, Western Cape, South Africa Placements24 Full-time

    Placements24 seeks a Lead Biologics Process Development Engineer in Cape Town to spearhead development and scale-up of biologics manufacturing processes. You will drive upstream/downstream optimization, pilot studies, and technology transfer with cross-functional teams focused on quality and efficiency.The role demands 7+ years in biologics development,...

  • Senior Architect

    21 hours ago


    Cape Town, Western Cape, South Africa Placements24 Remote Full-time

    About the RoleOur client, a visionary architectural practice focused on transformative urban regeneration and the creation of vibrant mixed-use developments, is seeking a Senior Architect to join their innovative team. This role, while based in Polokwane, Limpopo, offers significant flexibility and is designed to accommodate remote work arrangements,...


  • Cape Town, Western Cape, South Africa ATS Client Full-time

    ATS Client in Cape Town seeks an experienced SQL Developer to design, develop, and optimize complex SQL Server solutions. You will write efficient T-SQL, create stored procedures, views, and functions, and work on high-volume workloads.You will analyze execution plans, apply indexing and partitioning, design OLTP/3NF models, and collaborate with BI teams to...

  • Senior Civil Engineer

    21 hours ago


    Cape Town, Western Cape, South Africa Placements24 Remote Full-time

    About the Role Our client is seeking a highly skilled Senior Civil Engineer with extensive experience in site development and stormwater management for a fully remote position. This role will involve leading the design of complex site infrastructure projects, including grading, drainage, utility coordination, and erosion control. You will work with a diverse...


  • Cape Town, Western Cape, South Africa Placements24 Full-time

    Placements24 in Cape Town, Western Cape, is seeking a Senior Analytical Development Scientist for a hybrid role focused on developing and validating analytical methods (HPLC, UPLC, GC, MS, KF, dissolution, spectroscopy) for drug substances and products. You will characterize materials and ensure GMP compliance throughout the development lifecycle.Requires a...


  • Cape Town, Western Cape, South Africa Communicate IT Full-time R 420,000 - R 700,000 Contract

    Reference: CTI003434-CAF-1Are you a .NET developer with extraordinary skills and a burning passion for creating exceptional software solutions? We are on a quest to find a .NET developer who can harness the power of this versatile framework and take our client’s projects to new heights.Duties & ResponsibilitiesJob Description:As a .NET developer on our...


  • Cape Town, Western Cape, South Africa iDbase Software Full-time

    Duration: 12 Months ContractLocation: Cape TownJob Description - Senior .NET MAUI Developer (Android Terminal Application)The roleYou'll be one of two developers building a new Android terminal application from the ground up, targeting PAX payment devices in a fuel forecourt environment. The application consolidates fleet card processing, mobile money, cash...


  • Cape Town, Western Cape, South Africa Placements24 Full-time

    About the Role Our client, a leading Pharmaceutical organization, is seeking a highly skilled and motivated Senior Analytical Development Scientist to join their Research and Development team. This hybrid role, based in the vibrant city of Cape Town, Western Cape, ZA , is critical for the development and validation of robust analytical methods for...


  • Cape Town, Western Cape, South Africa ATS Client Full-time

    Job Description THE OPPORTUNITY THAT AWAITS YOU We're looking for an experienced Senior Front-End Developer to join a technology‑driven organisation where digital platforms play a critical role in business operations and customer experience. In this role, you'll contribute to the development and evolution of large‑scale business and customer‑facing...


  • Cape Town, Western Cape, South Africa Boardroom Appointments Full-time

    Senior Business Intelligence (BI) Developer (Level 3)Job Openings Senior Business Intelligence (BI) Developer (Level 3)About the job Senior Business Intelligence (BI) Developer (Level 3)Purpose: To lead the design, development, and deployment of advanced reporting and analytical solutions, providing expert insights to support and enhance business decisions...