Senior Statistical Programmer

Job Ad

Senior Statistical Programmer– Afternoon Shift (US Hours)

Work from our offices in Sandton, Durban, Cape Town, or Kenya

Afternoon Shift | 2PM – 11PM (US Hours)

About Us

talent match africa connects experienced professionals in Africa (just like you) with international employers from around the world (places like the USA, Australia, the UK, India, and Europe). Since 2016, we've been providing employability services to professionals across technology, finance, digital marketing, graphic design, and more. We currently have several permanent roles available at our offices in Johannesburg (Sandton) and Durban (Umhlanga), working for incredible international companies.

We are seeking an experienced
Senior Statistical Programmer
to join our client's clinical research team.

Key Responsibilities

Dataset Development & Validation

• Develop and validate CDISC-compliant datasets (SDTM & ADAM) for clinical trial studies using SAS
• Create SDTM specifications aligned with current SDTM standards
• Create ADAM specifications aligned with ADAM standards and industry best practices
• Develop and validate Tables, Listings and Figures (TLFs) for clinical trial data presentation

Programming & Analysis

• Develop, validate and maintain complex statistical programs using SAS, R, or similar platforms for data manipulation, analysis and reporting in clinical trials
• Perform SAS programming and quality control (QC) of analysis datasets, TFLs and standard tools following company standard data models and user requirements
• Conduct statistical analyses using various procedures and methodologies
• Integrate data across multiple studies in support of Clinical Study Synopsis (CSS) and Clinical Study Evaluation (CSE)

Collaboration & Documentation

• Collaborate closely with biostatisticians and cross-functional teams to interpret study requirements and ensure accurate implementation of statistical analyses
• Prepare and review Statistical Analysis Plans (SAPs), programming specifications and derived datasets to meet regulatory standards
• Create, manage and maintain programming specifications for analysis datasets utilising company tools and methodologies
• Support the creation and validation of regulatory submission requirements, including annotated CRFs, data export files, and documents

Quality & Compliance

• Ensure data integrity and compliance with industry regulations, including ICH/GCP guidelines, throughout the programming process
• Maintain adherence to CDISC standards and regulatory requirements across all deliverables

Leadership & Coordination

• Assist in coordinating programming activities and communicating shifting timelines and project milestones
• Mentor junior programmers and assist in training team members on programming techniques and best practices

Required Qualifications

Education

• Bachelor's degree in Statistics, Mathematics, Computer Science, or a related field
• Master's degree or advanced degree is highly desirable

Experience

• 3-5 years of end-to-end statistical programming experience
• Proven track record as a statistical programmer within the clinical research industry
• Strong knowledge of statistical methodologies and their application in clinical trials

Technical Skills

• Proficiency in SAS programming
  (essential)
• Experience with R or Python is advantageous
• Familiarity with clinical data management systems
• Strong understanding of CDISC standards (SDTM, ADAM, CDASH)
• Knowledge of regulatory submission requirements and processes

Core Competencies

• Strong analytical and problem-solving abilities with keen attention to detail
• Ability to work independently and manage multiple priorities effectively
• Excellent communication skills with the ability to convey complex statistical concepts to non-technical stakeholders
• Proven ability to collaborate effectively with cross-functional teams
• Commitment to quality, accuracy, and regulatory compliance

Where and how you can work:

Office Location:

To be successful, you'll need to:

• Work on-site from our office
• Be willing to work non-traditional local office hours.
• Be excited about a global opportunity with an international company.
• Have excellent written and verbal communication skills in English.

We make hiring decisions based on your experience, skills and passion, as well as how you can enhance our clients' businesses and their culture. When you apply, please tell us the pronouns you use and any reasonable adjustments you may need during the interview process.