Laboratory Manager

7 months ago

Cape Town, South Africa TASK Full time

**About the Company**:
TASK Laboratory is a core team within TASK, a clinical research institute and social enterprise, and is committed to state-of-the-art biological laboratory testing and providing these as a service during the development and progression of novelty medicines, vaccines and diagnostics, in particular the TB therapeutic area. TASK performs clinical trials at various sites in Cape Town and George, South Africa.

TASK Laboratory consists of biohazard-safety level 2 and 3 (BSL-2/3) laboratories, together with sample reception and media laboratories, and performs testing for drug susceptible and drug resistant TB, using established diagnostic methods and new research platforms.

**Overall Purpose of the Position**:
The Laboratory Manager oversees and manages all operations within the TASK laboratory (mycobacteriology, phage program and scientific streams). This encompasses planning, organizing, and supervising all testing procedures and subsequent analysis for studies conducted in the lab. The Laboratory Manager acts as the primary liaison between sponsors and the laboratory, ensuring that all work aligns with sponsors' requirements and the laboratory's capabilities while also fostering a collaborative and productive work environment for the laboratory staff within the larger TASK organisation. The Laboratory Manager is responsible for maintaining the facility to meet regulatory and ISO standards, ensuring a safe and efficient working environment for all personnel. Furthermore, the Manager provides scientific and technical guidance to the laboratory staff, serving as a leader in advancing research and maintaining high standards of quality and efficiency.

**Key Performance Areas (KPAs) & Responsibilities include, but not limited to**:

- Overseeing the daily operations of the laboratory, ensuring that all laboratory activities comply with the relevant policies, procedures and standards
- Ensuring project planning and implementation of all testing according to the trial plan for each study conducted through TASK Laboratory
- Managing laboratory budgets and expenditure, ordering of supplies and proactive maintenance of equipment, with consideration of cost/benefit/safety implications
- Ensuring that good quality, timely result data is consistently produced
- Providing expertise and reviewing and approving all laboratory standard operating procedures (SOPs)
- Managing and supporting laboratory management team with performance discussions, feedback, the provision of training opportunities and aligning individual goals with laboratory objectives. Enabling the laboratory to adhere to business standards, practices, procedures and protocol requirements
- Ensuring that the quality management system for the laboratory is in place and is being adhered to, ensuring the accuracy and reliability of laboratory results and investigating and resolving any issues relating to laboratory quality or safety
- Ensuring a safe and efficient working environment for all personnel with the adherence to all biosafety and biosecurity protocols, especially in the BSL-3 unit
- Preparing and presenting reports on laboratory activities, progress of research projects and compliance with safety regulations as required
- Facilitating effective communication within the laboratory team
- Ensuring that there are sufficient, appropriately trained staff and other resources in place to perform each study
- Monitoring trends, identifying significant project risks and dealing with potential problems before they occur. Ensuring idea-sharing and problem-solving among team members
- Contributing intellectually to the scientific direction of research projects and studies
- Maintaining and broadening the scope of the laboratory

**Ideal Requirements**
- MSc or PhD in (micro-)biology, chemistry, biochemistry or other health and science field
- At least five years’ experience in managing laboratory operations
- Basic project management skills to coordinate workflows, set priorities, and allocate resources efficiently to meet project deadlines and objectives. Experience in inventory management to track and maintain supplies, reagents, and consumables necessary for laboratory operations
- Knowledge of good clinical laboratory practice (GCLP) guidelines and regulations
- Understanding of QA/QC principles and practices to ensure accurate and reliable results
- Experience in clinical trials (advantageous)
- **Key Personal Inherent Characteristics**:

- Leads by example in line with TASK’s culture
- Excellent planning and organising skills, with the ability to work systematically and sequentially
- Personal effectiveness and the ability to work in a pressurised environment, with strict adherence to timelines
- Excellent communication and interpersonal skills
- Competent in identifying obstacles or problems and implementing an appropriate action plan
- Ability and willingness to adapt working hours in response to the business needs which may chan

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