Protein Expression and Purification Scientist

The purpose of the Protein Expression and Purification Scientist position is to oversee and perform all the activities associated with the development, expression, purification and analysis of diagnostic and therapeutic proteins

Minimum Requirements
- Masters degree in Biotechnology, Chemical Engineering or other relevant degree.
- PhD in Biotechnology preferred.
- Minimum of 3 years’ experience GMP or Biotechnology environment.
- Successful track record in the field of Biotechnology R&D project management.
- Broad experience in the analysis of complex formulations.
- Minimum of 3 years’ experience in protein expression and purification systems, with mammalian and bacterial cell culture experience preferred.
- Experience in synthesis, purification and analysis of synthetic peptides preferred.
- Experience in transfer of methods and data to other laboratories preferred.
- Any experience in plasma-derived therapeutic proteins is a plus

Specific Operational Requirements
- May be required to work overtime to meet the business needs.
- Must be prepared to work shifts/weekends/public holidays when needed

Specific SHE Requirements
- Pre-employment, routine, and exit medicals are compulsory due to the nature of the

business.
- Attendance to SHE-related training is mandatory.
- Adherence to SHE Instructions (Waste Segregation, Water and Energy Saving Initiatives)
- Compliance with SHE Site Rules is compulsory.

required to use proper PPE and will go through medical examinations as per OSH Act

requirements.

Key Performance Areas:
In collaboration with the Head of Biotechnology Product Development to:

- Equip, implement and maintain a well-resourced protein expression, purification and analysis

capability in the Product Development laboratory.
- Prepare User Requirement specifications to support the purchasing of the required process and

analytical equipment.
- Collaborate with internal stakeholders such as the Validation team to ensure equipment are

correctly installed, commissioned and qualified.
- Manage therapeutic protein development projects in terms of activities, timelines and

resources.
- Review scientific literature, abstracts, patents, and applicable laboratory methods as appropriate to prepare technical reports relating to identified development projects.
- Provide high level report back on protein expression and purification capabilities and progress.
- Participate in internal and external technology transfer projects to establish protein expression and purification capabilities and capacity.
- Collaborate with other functions/departments to improve existing pharmaceutical products and create new products.
- Participate in the planning and design of production areas for therapeutic product

manufacturing meeting GMP and other requirements.
- Ensure up to date knowledge of appropriate technologies in the biotechnology field as it related to biologics/biosimilars through extensive reading, research and maintaining and developing contacts with experts in the field.