Diagnostic Product Production Analyst

5 months ago


Pinetown, South Africa NBISA Recruitment Full time

**Job Advert Summary**:
To use as an individual, his/her academic background, training and experience to perform immunoassay, protein expression and purifications prescribed for the production and QC analysis of saleable monoclonal antibodies, recombinant antigens, ELISA kits and components.

Key results areas:

- QC testing of ELISA reagents, components and final kits
- Recombinant Antigen Production and quality analysis
- QC analysis of NBI saleable monoclonal antibodies
- Laboratory resourcing and equipment maintenance

**Minimum Requirements**:

- Essential: BSc in Biochemistry, Microbiology
- Preferred: BSc Honours in Biochemistry, Microbiology
- 2-3 years ELISA experience and
- 2-3 years recombinant protein expression and purification experience

**Duties and Responsibilities**:
**QC testing of ELISA reagents, components and final kits.**
- QC testing of all ELISA reagents, components and final kits during the different production stags.
- Perform QC procedures on the following ELISA components:

- EPU Coated ELISA plates
- In-process testing on the hyperimmune

coated plates.
- Hyperimmune conjugates
- All ELISA components (2% Bosine,

Conjugate Diluent, Sulphuric acid,

Chromogenic substrate, Controls and

Standards).
- Complete documentation for all kit components, upload results into LIMS and send to QARM analyst for signing off and authorization in LIMS and final release in SAP.
- Complete documentation for final kits and upload into SAP, send to QARM analyst for SAP upload and to Head: DPP for SAP authorization and to internal Auditor for review and Head: QA for final release of the ELISA kits in SAP.
- Perform test and method validations according to internal DPP program.
- Trouble shooting of hyperimmune ELISA kits for QARM to resolve quality issues.

**Production and QC testing of recombinant antigens associated with saleable monoclonal antibodies**
- Produce recombinant proteins to support monoclonal antibody production of saleable antibodies.
- QC test to validate activity, specificity and coating concentration of produced recombinant antigens

**QC analysis of NBI saleable monoclonal antibodies**
- Perform QC analysis on purified saleable monoclonal antibodies using sds-page gel electrophoresis and determine the antibody purity by densitometric analysis using gel imaging software.
- Provide mAb purity and gel result documentation to Section Head: Antibody Production to complete final release of NBI monoclonal antibodies.

***Laboratory resourcing and equipment maintenance**
- Maintain laboratory equipment and cleanliness
- Maintain chemical and operational consumable stock levels.
- Ensure compliance with ISO13485 standards.
- Perform the general housekeeping of the laboratory.

**Core Competencies**
- Managing Relationships
- Personal Leadership
- Business Impact
- Leading and Influencing others Technical/Professional knowledge and proficiency
- Knowledge of ISO13485 quality system
- Technical/Professional knowledge and proficiency
- Planning and organising
- Attention to Detail and analysis
- Written and verbal communication
- Computer Literacy in MS Office, SAP and LIMS
- Experience in immunoassays, design and trouble-shooting ELISA’s
- Collaboration and teamwork



  • Pinetown, South Africa NBISA Recruitment Full time

    **Job Advert Summary**: Guided by its purpose to provide products for patients to alleviate pain and suffering and improve their quality of life, NBI’s vision is to be the leading African manufacturer and supplier of quality therapeutic proteins and diagnostic products. National Bioproducts Institute NPC has a vacancy for the role of Head: Biotechnology...

  • Product Consultant Kzn

    2 months ago


    Pinetown, South Africa NBISA Recruitment Full time

    **Job Advert Summary**: Guided by its purpose to provide products for patients to alleviate pain and suffering and improve their quality of life, NBI’s vision is to be the leading African manufacturer and supplier of quality therapeutic proteins and diagnostic products. National Bioproducts Institute NPC has a vacancy for the role of Product Consultant....

  • Production Manager

    4 months ago


    Pinetown, South Africa ARTsolar Full time

    **PRODUCTION MANAGER** DUTIES: - Manage a team of up to operators spread across up to 4 shifts, which each shift including production supervisor(s) and team leader(s) in a high-volume manufacturing environment. - Create and maintain contingency plans in the event of interruptive production - Manage use of raw materials to meet production targets as set out...

  • Production Manager

    5 months ago


    Pinetown, South Africa ARTsolar Full time

    **PRODUCTION MANAGER** DUTIES: - Manage a team of up to operators spread across up to 4 shifts, which each shift including production supervisor(s) and team leader(s) in a high-volume manufacturing environment. - Create and maintain contingency plans in the event of interruptive production - Manage use of raw materials to meet production targets as set out...

  • Production Manager

    3 weeks ago


    Pinetown, KwaZulu-Natal, South Africa CDI HR Consulting Full time

    Job DescriptionOur client, a well-established Chemical Manufacturer, is seeking a strong candidate to manage a team of around 20 staff within various manufacturing units. This role will report into the Production Manager for the site and will be responsible for ensuring all team members adhere to quality and safety standards.Key Responsibilities:Manage a...

  • Production Manager

    5 months ago


    Pinetown, South Africa Unique Personnel Full time

    **Job Number** - 73005 **Job Type** - Permanent **Job Title** - Production Manager **Computer Skills** - MS Excel **Industry** - Manufacturing **City** - Pinetown **Province** - Kwazulu Natal **Performance Outputs** **Planning** - Liaise with Operations Manager re current projections vs. actual sales - Review/ adjust monthly Planning Schedule &...

  • Production Manager

    5 months ago


    Pinetown, South Africa re|source consulting Full time

    A leading manufacturer in the packaging sector has an opportunity for an energetic, self-motivated Mechanical/Electrical Engineer with experience in a fast-paced, continuous production environment to lead their Production Team, based in Pinetown. This role will suit someone who has a passion for production, people and striving for excellence, and is looking...

  • Production Planner

    9 hours ago


    Pinetown, South Africa Staff Unlimited Recruitment Full time

    My client in the FMCG industry is seeking to employ a Production Planner to join their company based in Pinetown. Candidate must be able to work in a fast-paced environment Duties include:Issue weekly production schedules for production requirementsEnsuring there is sufficient finished goods stock to fulfill orders, and reorder levels are maintainedManage...

  • Production Manager

    5 months ago


    Pinetown, South Africa Pedros Flame Grilled Chicken Full time

    **DUTIES AND RESPONSIBILITIES**: - Ensure that all bay areas stock is kept and clearly labelled. - There is a space at all times for discontinued/discarded/damaged stock. - Ensure stock take SOP is strictly adhered to. - Ensure all SOPs are followed. - Ensure PARS are maintained, if not communicate potential shortcomings at least 2 days in advance. - All...

  • Product Trainer

    5 months ago


    Pinetown, South Africa PikUniq Full time

    A company that deals with Fleet Management Software Solutions is looking for someone with an entrepreneurial drive, who can take ownership, embrace challenges and love problem-solvin. **Responsibility**: - Train clients and internal staff on the use of the Fleet Pages. - Assist with Training on unit testing, identify training requirements and research and...

  • Production Planner

    2 months ago


    Pinetown, South Africa Ad hoc Full time

    As a Production Planner, you are responsible for **scheduling and coordinating the manufacturing process** to increase efficiency, minimize waste, and optimize resources. You must have expertise in planning, organizing, and evaluating production schedules, raw materials, and labour requirements. Key Responsibilities: - Production Planning - Materials...

  • Production Team Leader

    5 months ago


    Pinetown, South Africa AVI Limited Full time

    **AVI Ltd. **is known for its leading household brands across many categories including: hot beverages, sweet and savoury biscuits and snacks, frozen convenience foods, personal care products, cosmetics, shoes, accessories, and fashion apparel. **NATIONAL BRANDS LIMITED** operates 5 manufacturing sites, offering world class manufacturing facilities in...


  • Pinetown, South Africa TNT Recruitment Full time

    Fast growing, Pinetown based clothing manufacturing company seeks a detail oriented Product Coordinator. **Requirements**: 5 years experience in the same or relevant role. Overseeing the production process and ensuring production is cost effective Drawing up a production schedule and making sure that products are produced on time and are of good...


  • Pinetown, South Africa Crew Life at Sea Full time

    Key Responsibilities: - Assist the Production Manager in planning and scheduling all entertainment and activities **on board a cruise ship** - Coordinate with various departments to ensure smooth execution of all shows and events - Oversee the recruitment, training, and management of production staff, including performers, technicians, and other crew...


  • Pinetown, South Africa Continental Engineering Compounds Full time

    **Position Summary**: The Shift Supervisor is responsible and accountable for optimum functioning of their shift, to ensure production targets are managed daily whilst generating minimum waste. They will oversee all functions including equipment, machinery, product, quality and staffing. They are accountable to the Production Manager. **KEY PERFORMANCE...


  • Pinetown, South Africa Continental Engineering Compounds Full time

    **Position Summary**: The Shift Supervisor is responsible and accountable for optimum functioning of their shift, to ensure production targets are managed daily whilst generating minimum waste. They will oversee all functions including equipment, machinery, product, quality and staffing. They are accountable to the Production Manager. **KEY PERFORMANCE...


  • Pinetown, South Africa Home of Living Brands Full time

    Manufacturing and quality: - Daily product plan is met. - Quality control is managed, and inspection is in line with or SLA and return rate target % set by the company. - Effectively managing and negotiating the cost of the product with the supplier and updating the Factory transfer price (FTP). - Quality assurance: Manage the ISO9001 certificate and...


  • Pinetown, South Africa SRG Recruitment Full time

    Overview (Area:) Pinetown (Salary:) Market Related (Ref: AG) Our client seeks to appoint a suitably experienced and qualified Flexographic Production Manager to ensure the efficient and timely production of products, produced within budget and within industry standards, staff and plant management as well as streamlining processes for operational...

  • Production Supervisor

    4 months ago


    Pinetown, South Africa SRG Recruitment Full time

    Overview (Area:) Pinetown (Salary:) Market Related (Ref: AG) Our client seeks to appoint a suitably qualified and experienced Production Supervisor from the automotive manufacturing sector to supervise the safe execution of all activities in the manufacturing processes and to ensure the achievement of production and quality targets. Must have 5+ years’...


  • Pinetown, South Africa TNT Recruitment Full time

    Fast growing, Pinetown based clothing manufacturing company seeks a detail oriented Product Coordinator. **Requirements**: 5 years experience in the same or relevant role. Overseeing the production process and ensuring production is cost effective Drawing up a production schedule and making sure that products are produced on time and are of good...